{"id":19253,"date":"2024-11-13T16:40:02","date_gmt":"2024-11-13T08:40:02","guid":{"rendered":"https:\/\/landu-china.com\/?p=19253"},"modified":"2024-11-13T16:54:23","modified_gmt":"2024-11-13T08:54:23","slug":"hydroxypropylmetylceluloza-hpmc-vo-farmaceutickych-aplikaciach","status":"publish","type":"post","link":"https:\/\/landu-china.com\/sk\/hydroxypropylmetylceluloza-hpmc-vo-farmaceutickych-aplikaciach\/","title":{"rendered":"Hydroxypropylmetylcelul\u00f3za (HPMC) vo farmaceutick\u00fdch aplik\u00e1ci\u00e1ch"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"19253\" class=\"elementor elementor-19253\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8ed4792 e-flex e-con-boxed e-con e-parent\" data-id=\"8ed4792\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-27bb47c5 e-con-full e-flex e-con e-child\" data-id=\"27bb47c5\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5745a1aa elementor-widget elementor-widget-heading\" data-id=\"5745a1aa\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Hydroxypropylmetylcelul\u00f3za (HPMC) vo farmaceutick\u00fdch aplik\u00e1ci\u00e1ch<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5f276119 elementor-tablet-align-center elementor-widget elementor-widget-post-info\" data-id=\"5f276119\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"post-info.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-inline-items elementor-icon-list-items elementor-post-info\">\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-8a4e3ed elementor-inline-item\" itemprop=\"datePublished\">\n\t\t\t\t\t\t<a href=\"https:\/\/landu-china.com\/sk\/2024\/11\/13\/\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-far-calendar\" viewbox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M400 64h-48V12c0-6.6-5.4-12-12-12h-40c-6.6 0-12 5.4-12 12v52H160V12c0-6.6-5.4-12-12-12h-40c-6.6 0-12 5.4-12 12v52H48C21.5 64 0 85.5 0 112v352c0 26.5 21.5 48 48 48h352c26.5 0 48-21.5 48-48V112c0-26.5-21.5-48-48-48zm-6 400H54c-3.3 0-6-2.7-6-6V160h352v298c0 3.3-2.7 6-6 6z\"><\/path><\/svg>\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-date\">\n\t\t\t\t\t\t\t\t\t\t<time>13. novembra 2024<\/time>\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t<\/li>\n\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-271dd1a elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"271dd1a\" data-element_type=\"section\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<main class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-2d5bb40\" data-id=\"2d5bb40\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-38c4036 elementor-widget elementor-widget-text-editor\" data-id=\"38c4036\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Hydroxypropylmetylcelul\u00f3za (HPMC), univerz\u00e1lny polym\u00e9r zn\u00e1my svojimi v\u00fdnimo\u010dn\u00fdmi vlastnos\u0165ami, zohr\u00e1va vo farmaceutickom priemysle k\u013e\u00fa\u010dov\u00fa \u00falohu. Ako chemicky modifikovan\u00fd \u00e9ter celul\u00f3zy sa HPMC vyzna\u010duje stabilitou, biokompatibilitou a vynikaj\u00facimi filmotvorn\u00fdmi schopnos\u0165ami. V\u010faka t\u00fdmto vlastnostiam je HPMC preferovanou vo\u013ebou v \u0161irokom spektre farmaceutick\u00fdch pr\u00edpravkov, najm\u00e4 v peror\u00e1lnych liekov\u00fdch form\u00e1ch, pr\u00edpravkoch s riaden\u00fdm uvo\u013e\u0148ovan\u00edm a povlakoch. V tomto \u010dl\u00e1nku sa budeme venova\u0165 r\u00f4znym pou\u017eitiam, v\u00fdhod\u00e1m a funk\u010dn\u00fdm aplik\u00e1ci\u00e1m HPMC vo farmaceutickom priemysle a poskytneme v\u00e1m komplexn\u00e9 pochopenie toho, pre\u010do je tento materi\u00e1l tak \u0161iroko roz\u0161\u00edren\u00fd v tomto odvetv\u00ed.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2783d7f elementor-widget elementor-widget-heading\" data-id=\"2783d7f\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\u010co je HPMC? Stru\u010dn\u00fd preh\u013ead<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-26892db elementor-widget elementor-widget-text-editor\" data-id=\"26892db\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>HPMC alebo <strong>Hydroxypropylmetylcelul\u00f3za<\/strong>je polosyntetick\u00fd, inertn\u00fd a vo vode rozpustn\u00fd polym\u00e9r odvoden\u00fd od celul\u00f3zy. HPMC sa vyr\u00e1ba \u00fapravou celul\u00f3zy metylchloridom a propyl\u00e9noxidom a vytv\u00e1ra stabiln\u00fd celul\u00f3zov\u00fd \u00e9ter, ktor\u00fd si zachov\u00e1va svoju \u0161trukt\u00faru v \u0161irokom rozsahu pH a pri r\u00f4znych teplotn\u00fdch podmienkach. V\u010faka t\u00fdmto vlastnostiam sa HPMC \u010dasto pou\u017e\u00edva vo farmaceutick\u00fdch pr\u00edpravkoch, ktor\u00e9 vy\u017eaduj\u00fa stabilitu, konzistentn\u00e9 profily uvo\u013e\u0148ovania a vlastnosti vhodn\u00e9 pre pacienta.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-56c3687 elementor-widget elementor-widget-heading\" data-id=\"56c3687\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Chemick\u00e9 vlastnosti HPMC\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a15de8b elementor-widget elementor-widget-text-editor\" data-id=\"a15de8b\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Vlastnosti HPMC ho robia jedine\u010dn\u00fdm medzi \u00e9termi celul\u00f3zy. Medzi jeho k\u013e\u00fa\u010dov\u00e9 vlastnosti patria:<\/p><ul><li><strong>Rozpustnos\u0165:<\/strong> HPMC je rozpustn\u00fd vo vode a vytv\u00e1ra prieh\u013eadn\u00e9 roztoky s vysokou viskozitou.<\/li><li><strong>Viskozita:<\/strong> Viskozita je nastavite\u013en\u00e1 v r\u00f4znych triedach, \u010do vyhovuje r\u00f4znym farmaceutick\u00fdm aplik\u00e1ci\u00e1m.<\/li><li><strong>Tepeln\u00e1 gel\u00e1cia:<\/strong> HPMC vykazuje tepeln\u00fa gel\u00e1ciu, ktor\u00e1 mu umo\u017e\u0148uje vytv\u00e1ra\u0165 g\u00e9ly pri \u0161pecifick\u00fdch teplot\u00e1ch, \u010do je u\u017eito\u010dn\u00e9 v syst\u00e9moch s riaden\u00fdm uvo\u013e\u0148ovan\u00edm.<\/li><li><strong>Stabilita pH:<\/strong> HPMC zost\u00e1va stabiln\u00fd pri hodnot\u00e1ch pH typick\u00fdch pre \u017eal\u00fado\u010dn\u00e9 aj \u010drevn\u00e9 tekutiny, v\u010faka \u010domu je vhodn\u00fd na peror\u00e1lne pod\u00e1vanie lie\u010div.<\/li><\/ul><p>Chemick\u00e1 \u0161trukt\u00fara HPMC mu poskytuje flexibilitu pri pou\u017e\u00edvan\u00ed a v\u00fdkone, v\u010faka \u010domu je z\u00e1kladnou zlo\u017ekou vo farmaceutickom sektore.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-830780d elementor-widget elementor-widget-heading\" data-id=\"830780d\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Pou\u017eitie HPMC vo farmaceutick\u00fdch v\u00fdrobkoch\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b097541 elementor-widget elementor-widget-heading\" data-id=\"b097541\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">1. Matricov\u00e9 syst\u00e9my s riaden\u00fdm uvo\u013e\u0148ovan\u00edm<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4496db9 elementor-widget elementor-widget-text-editor\" data-id=\"4496db9\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>HPMC sa \u0161iroko pou\u017e\u00edva v pr\u00edpravkoch s riaden\u00fdm uvo\u013e\u0148ovan\u00edm. Jeho schopnos\u0165 vytv\u00e1ra\u0165 g\u00e9ly po hydrat\u00e1cii umo\u017e\u0148uje dlhodob\u00e9 uvo\u013e\u0148ovanie akt\u00edvnych farmaceutick\u00fdch zlo\u017eiek (API). Ako hydrofiln\u00fd matricov\u00fd materi\u00e1l HPMC pri kontakte s gastrointestin\u00e1lnymi tekutinami napu\u010diava a vytv\u00e1ra g\u00e9lov\u00fa bari\u00e9ru, ktor\u00e1 spoma\u013euje r\u00fdchlos\u0165 uvo\u013e\u0148ovania lie\u010diva. T\u00e1to vlastnos\u0165 je obzvl\u00e1\u0161\u0165 cenn\u00e1 pri liekoch, ktor\u00e9 si vy\u017eaduj\u00fa pred\u013a\u017een\u00fd alebo trval\u00fd terapeutick\u00fd \u00fa\u010dinok, \u010d\u00edm sa zvy\u0161uje compliance pacienta a zni\u017euje frekvencia d\u00e1vkovania.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-d9317fe elementor-section-boxed elementor-section-height-default elementor-section-height-default elementor-invisible\" data-id=\"d9317fe\" data-element_type=\"section\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;,&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-8837c1a\" data-id=\"8837c1a\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-056a3f3 elementor-widget elementor-widget-spacer\" data-id=\"056a3f3\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-8c060fb\" data-id=\"8c060fb\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f156195 elementor-widget elementor-widget-spacer\" data-id=\"f156195\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-610c6cf elementor-widget elementor-widget-heading\" data-id=\"610c6cf\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">2. Prostriedok na nan\u00e1\u0161anie f\u00f3lie<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-aa3b745 elementor-widget elementor-widget-text-editor\" data-id=\"aa3b745\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>V\u010faka svojim filmotvorn\u00fdm vlastnostiam je HPMC vynikaj\u00facou vo\u013ebou pre <strong>po\u0165ahovanie tabliet<\/strong>. Filmov\u00e9 n\u00e1tery sa pou\u017e\u00edvaj\u00fa na ochranu \u00fa\u010dinn\u00fdch l\u00e1tok, zv\u00fd\u0161enie stability a zabezpe\u010denie le\u0161ten\u00e9ho vzh\u013eadu. Obaly HPMC tie\u017e pom\u00e1haj\u00fa maskova\u0165 chu\u0165 hork\u00fdch API a u\u013eah\u010duj\u00fa preh\u013atanie. Okrem toho m\u00f4\u017eu by\u0165 tieto povlaky navrhnut\u00e9 na enterick\u00e9 uvo\u013e\u0148ovanie, \u010d\u00edm sa zabezpe\u010d\u00ed, \u017ee sa lie\u010divo rozpust\u00ed sk\u00f4r v \u010dreve ako v \u017eal\u00fadku, \u010do je u\u017eito\u010dn\u00e9 najm\u00e4 pre lie\u010div\u00e1 citliv\u00e9 na kysl\u00e9 prostredie.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-55f9fda elementor-widget elementor-widget-heading\" data-id=\"55f9fda\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">3. Spojivo v tablet\u00e1ch a kapsul\u00e1ch\n<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-aa4aede elementor-widget elementor-widget-text-editor\" data-id=\"aa4aede\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Ako <strong>viaza\u010d<\/strong>, HPMC pom\u00e1ha konsolidova\u0165 \u0161trukt\u00faru tabliet, zlep\u0161uje s\u00fadr\u017enos\u0165 a mechanick\u00fa pevnos\u0165. To je nevyhnutn\u00e9 na dosiahnutie tabliet s dostato\u010dnou tvrdos\u0165ou pri zachovan\u00ed primeran\u00fdch dezintegra\u010dn\u00fdch vlastnost\u00ed. Viazacia schopnos\u0165 HPMC umo\u017e\u0148uje konzistentn\u00e9 d\u00e1vkovanie a rovnomernos\u0165, ktor\u00e9 s\u00fa pre farmaceutick\u00e9 v\u00fdrobky k\u013e\u00fa\u010dov\u00e9.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8650f24 elementor-widget elementor-widget-heading\" data-id=\"8650f24\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">4. Emulg\u00e1tor a stabiliz\u00e1tor v kvapaln\u00fdch pr\u00edpravkoch<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2deb52e elementor-widget elementor-widget-text-editor\" data-id=\"2deb52e\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Na str\u00e1nke <strong>suspenzie a emulzie<\/strong>, HPMC p\u00f4sob\u00ed ako <strong>emulga\u010dn\u00e9 a stabiliza\u010dn\u00e9 \u010dinidlo<\/strong>, \u010d\u00edm sa zabezpe\u010d\u00ed homogenita a stabilita tekut\u00fdch farmaceutick\u00fdch v\u00fdrobkov. Jeho schopnos\u0165 vytv\u00e1ra\u0165 koloidn\u00e9 disperzie prispieva k suspendovaniu nerozpustn\u00fdch \u010dast\u00edc, \u010do umo\u017e\u0148uje rovnomern\u00fa distrib\u00faciu a konzistentn\u00e9 d\u00e1vkovanie.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-037b4ef elementor-widget elementor-widget-heading\" data-id=\"037b4ef\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">5. Bioadhez\u00edvum na slizni\u010dn\u00e9 pod\u00e1vanie\n<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b414dde elementor-widget elementor-widget-text-editor\" data-id=\"b414dde\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Pri slizni\u010dnom pod\u00e1van\u00ed liekov, <strong>HPMC p\u00f4sob\u00ed ako bioadhez\u00edvum<\/strong>, \u010do umo\u017e\u0148uje pri\u013enutie lie\u010div na slizni\u010dn\u00e9 povrchy (napr. \u00fastnu, nosov\u00fa alebo o\u010dn\u00fa sliznicu). T\u00e1to vlastnos\u0165 zlep\u0161uje reten\u010dn\u00fd \u010das lie\u010div na mieste aplik\u00e1cie, \u010d\u00edm sa zvy\u0161uje absorpcia a biologick\u00e1 dostupnos\u0165, najm\u00e4 v pr\u00edpade lie\u010div s n\u00edzkou syst\u00e9movou absorpciou.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3c52c28 elementor-widget elementor-widget-heading\" data-id=\"3c52c28\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">V\u00fdhody pou\u017e\u00edvania HPMC vo farmaceutick\u00fdch pr\u00edpravkoch\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-af9365c elementor-widget elementor-widget-text-editor\" data-id=\"af9365c\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3><strong>Zv\u00fd\u0161en\u00e1 stabilita<\/strong><\/h3><p>HPMC zost\u00e1va stabiln\u00fd pri r\u00f4znych podmienkach skladovania a chr\u00e1ni API pred vlhkos\u0165ou a zmenami prostredia. T\u00e1to stabilita je rozhoduj\u00faca pre zachovanie \u00fa\u010dinnosti citliv\u00fdch liekov a dosiahnutie dlh\u0161ej doby skladovania.<\/p><h3><strong>Biokompatibilita<\/strong><\/h3><p>HPMC je <strong>netoxick\u00e9, nedr\u00e1\u017ediv\u00e9<\/strong>a <strong>biokompatibiln\u00e9<\/strong>, tak\u017ee je ide\u00e1lny na farmaceutick\u00e9 pou\u017eitie. Jeho inertn\u00fd charakter zni\u017euje riziko ne\u017eiaducich reakci\u00ed, \u010d\u00edm zabezpe\u010duje bezpe\u010dnos\u0165 a pohodlie pacienta, najm\u00e4 pri chronickej alebo dlhodobej lie\u010dbe.<\/p><h3><strong>Riaden\u00e9 uvo\u013e\u0148ovanie lie\u010div<\/strong><\/h3><p>Tepeln\u00e9 g\u00e9lovacie a hydrata\u010dn\u00e9 vlastnosti HPMC prispievaj\u00fa k <strong>riaden\u00e9 uvo\u013e\u0148ovanie<\/strong> mechanizmy. Modul\u00e1ciou viskozity HPMC pou\u017eit\u00e9ho v pr\u00edpravkoch m\u00f4\u017eu farmaceutick\u00ed vedci navrhn\u00fa\u0165 prisp\u00f4soben\u00e9 profily uvo\u013e\u0148ovania, ktor\u00e9 s\u00fa v s\u00falade s terapeutick\u00fdmi po\u017eiadavkami.<\/p><h3><strong>Maskovanie chuti a zlep\u0161enie estetiky<\/strong><\/h3><p>HPMC povlaky umo\u017e\u0148uj\u00fa <strong>maskovanie chuti<\/strong> v liekoch s nepr\u00edjemnou chu\u0165ou. M\u00f4\u017eu tie\u017e zv\u00fd\u0161i\u0165 estetick\u00fd vzh\u013ead tabliet, \u010d\u00edm sa u\u013eah\u010d\u00ed ich preh\u013atanie a stan\u00fa sa prijate\u013enej\u0161\u00edmi pre pacientov.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-34ed0ad elementor-widget elementor-widget-heading\" data-id=\"34ed0ad\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Triedy HPMC na farmaceutick\u00e9 pou\u017eitie\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cd8e2f2 elementor-widget elementor-widget-text-editor\" data-id=\"cd8e2f2\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>HPMC je k dispoz\u00edcii v r\u00f4znych triedach, rozdelen\u00fdch pod\u013ea viskozity a typu substit\u00facie, \u010do umo\u017e\u0148uje prisp\u00f4sobenie aplik\u00e1ci\u00ed:<\/p><ul><li><strong>Triedy s n\u00edzkou viskozitou<\/strong>: Zvy\u010dajne sa pou\u017e\u00edva v <strong>kvapaln\u00e9 pr\u00edpravky<\/strong> a ako spojiv\u00e1 v tablet\u00e1ch a kapsul\u00e1ch.<\/li><li><strong>Triedy so strednou viskozitou<\/strong>: Be\u017ene sa pou\u017e\u00edva v <strong>syst\u00e9my s riaden\u00fdm uvo\u013e\u0148ovan\u00edm<\/strong> v\u010faka ich vyv\u00e1\u017een\u00fdm g\u00e9lotvorn\u00fdm vlastnostiam.<\/li><li><strong>Triedy s vysokou viskozitou<\/strong>: Ide\u00e1lne pre <strong>filmov\u00e9 povlaky<\/strong> a aplik\u00e1cie s pred\u013a\u017een\u00fdm uvo\u013e\u0148ovan\u00edm, kde sa vy\u017eaduje siln\u00e1 g\u00e9lov\u00e1 matrica.<\/li><\/ul><p>Ka\u017ed\u00e1 trieda sl\u00fa\u017ei na \u0161pecifick\u00e9 \u00fa\u010dely a poskytuje flexibilitu pri navrhovan\u00ed farmaceutick\u00fdch v\u00fdrobkov s po\u017eadovan\u00fdmi vlastnos\u0165ami.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-3b43c66 elementor-section-boxed elementor-section-height-default elementor-section-height-default elementor-invisible\" data-id=\"3b43c66\" data-element_type=\"section\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;,&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-56798be\" data-id=\"56798be\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-670ea93 elementor-widget elementor-widget-spacer\" data-id=\"670ea93\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-8770651\" data-id=\"8770651\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-356731a elementor-widget elementor-widget-spacer\" data-id=\"356731a\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-a56c512 elementor-widget elementor-widget-heading\" data-id=\"a56c512\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">HPMC vs. in\u00e9 polym\u00e9ry vo farmaceutickom priemysle\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ade00fa e-con-full e-flex e-con e-child\" data-id=\"ade00fa\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b21bb1b elementor-widget elementor-widget-text-editor\" data-id=\"b21bb1b\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>HPMC m\u00e1 oproti alternat\u00edvnym polym\u00e9rom nieko\u013eko v\u00fdhod:<\/p><ul><li><strong>PVP (polyvinylpyrolid\u00f3n)<\/strong>: PVP sa s\u00edce tie\u017e pou\u017e\u00edva ako spojivo, ale nem\u00e1 tak\u00e9 vlastnosti ako HPMC, najm\u00e4 pri aplik\u00e1ci\u00e1ch s vysokou viskozitou.<\/li><li><strong>PEG (polyetyl\u00e9nglykol)<\/strong>: PEG s\u00fa rozpustn\u00e9 vo vode, ale nemaj\u00fa rovnak\u00fa mechanick\u00fa pevnos\u0165 a stabilitu v pevn\u00fdch liekov\u00fdch form\u00e1ch ako HPMC.<\/li><li><strong>Polym\u00e9ry Eudragit<\/strong>: Tie sa \u010dasto pou\u017e\u00edvaj\u00fa na enterick\u00e9 povlaky, ale nemaj\u00fa bioadhez\u00edvne a hydrofiln\u00e9 vlastnosti matrice, ktor\u00e9 robia HPMC univerz\u00e1lnym v r\u00f4znych syst\u00e9moch pod\u00e1vania lie\u010div.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c37d892 elementor-widget elementor-widget-heading\" data-id=\"c37d892\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">V\u00fdzvy spojen\u00e9 s pou\u017e\u00edvan\u00edm HPMC vo farmaceutick\u00fdch v\u00fdrobkoch\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c79d32e elementor-widget elementor-widget-text-editor\" data-id=\"c79d32e\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3><strong>V\u00fdzvy s\u00favisiace s formul\u00e1ciou<\/strong><\/h3><p>Vytvorenie liekov s riaden\u00fdm uvo\u013e\u0148ovan\u00edm pomocou HPMC si vy\u017eaduje presnos\u0165. Faktory ako koncentr\u00e1cia HPMC, rozpustnos\u0165 lie\u010diva a ve\u013ekos\u0165 \u010dast\u00edc zohr\u00e1vaj\u00fa \u00falohu v tom, ako dobre bude v\u00fdsledn\u00fd produkt fungova\u0165.<\/p><h3><strong>N\u00e1klady<\/strong><\/h3><p>Vysokokvalitn\u00fd HPMC m\u00f4\u017ee by\u0165 drah\u0161\u00ed ako in\u00e9 pomocn\u00e9 l\u00e1tky, ale jeho v\u00fdhody pri formul\u00e1ci\u00e1ch s riaden\u00fdm uvo\u013e\u0148ovan\u00edm, stabilita a pohodlie pacienta \u010dasto prevy\u0161uj\u00fa n\u00e1klady.<\/p><h3><strong>Konzistencia g\u00e9lovej vrstvy<\/strong><\/h3><p>G\u00e9lov\u00e1 vrstva HPMC je nevyhnutn\u00e1 pre riaden\u00e9 uvo\u013e\u0148ovanie, ale mus\u00ed by\u0165 starostlivo riaden\u00e1. Ak sa g\u00e9l netvor\u00ed d\u00f4sledne, m\u00f4\u017ee to ma\u0165 vplyv na r\u00fdchlos\u0165 uvo\u013e\u0148ovania lieku. Pri starostlivom zlo\u017een\u00ed sa v\u0161ak tento probl\u00e9m d\u00e1 zvl\u00e1dnu\u0165.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0b837a0 elementor-widget elementor-widget-heading\" data-id=\"0b837a0\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Bud\u00facnos\u0165 HPMC vo farmaceutickom priemysle\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0d79a84 elementor-widget elementor-widget-text-editor\" data-id=\"0d79a84\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3><strong>Aplik\u00e1cie nanotechnol\u00f3gi\u00ed<\/strong><\/h3><p>Biokompatibilita HPMC ho rob\u00ed s\u013eubn\u00fdm pre <strong>syst\u00e9my na pod\u00e1vanie lie\u010div na b\u00e1ze nano\u010dast\u00edc<\/strong>. Tieto syst\u00e9my zlep\u0161uj\u00fa vstreb\u00e1vanie liekov a zvy\u0161uj\u00fa ich \u00fa\u010dinnos\u0165, najm\u00e4 pri n\u00e1ro\u010dn\u00fdch terapi\u00e1ch.<\/p><h3><strong>Udr\u017eate\u013en\u00e1 v\u00fdroba<\/strong><\/h3><p>Ke\u010f\u017ee sa udr\u017eate\u013enos\u0165 dost\u00e1va do popredia, spolo\u010dnosti sk\u00famaj\u00fa sp\u00f4soby v\u00fdroby HPMC s men\u0161\u00edm vplyvom na \u017eivotn\u00e9 prostredie. Tento posun zah\u0155\u0148a ekologick\u00e9 v\u00fdrobn\u00e9 procesy a udr\u017eate\u013en\u00e9 z\u00e1sobovanie.<\/p><h3><strong>Personalizovan\u00e1 medic\u00edna<\/strong><\/h3><p>Ke\u010f\u017ee zdravotn\u00e1 starostlivos\u0165 smeruje k <strong>personalizovan\u00e1 medic\u00edna<\/strong>, HPMC je v\u010faka svojim prisp\u00f4sobiv\u00fdm vlastnostiam vhodnou vo\u013ebou na vytv\u00e1ranie vlastn\u00fdch liekov\u00fdch profilov prisp\u00f4soben\u00fdch individu\u00e1lnym potreb\u00e1m pacienta.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c4f93d6 elementor-widget elementor-widget-spacer\" data-id=\"c4f93d6\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-718fb18 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"718fb18\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-9e8fcf0 elementor-section-boxed elementor-section-height-default elementor-section-height-default elementor-invisible\" data-id=\"9e8fcf0\" data-element_type=\"section\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;,&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-0af88b8\" data-id=\"0af88b8\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6ffd5ff elementor-widget elementor-widget-heading\" data-id=\"6ffd5ff\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Kontaktujte n\u00e1s a z\u00edskajte vzorky zadarmo<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c66d934 elementor-widget elementor-widget-text-editor\" data-id=\"c66d934\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tPros\u00edm, kontaktujte ma pre najnov\u0161iu cenov\u00fa ponuku alebo pre vy\u017eiadanie vzorky (na\u0161e vzorky s\u00fa zadarmo a zah\u0155\u0148aj\u00fa dopravu).\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ca311cc elementor-button-align-stretch elementor-widget elementor-widget-form\" data-id=\"ca311cc\" data-element_type=\"widget\" data-settings=\"{&quot;step_next_label&quot;:&quot;Next&quot;,&quot;step_previous_label&quot;:&quot;Previous&quot;,&quot;button_width&quot;:&quot;100&quot;,&quot;step_type&quot;:&quot;number_text&quot;,&quot;step_icon_shape&quot;:&quot;circle&quot;,&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"form.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<form class=\"elementor-form\" method=\"post\" name=\"New Form\" action=\"\">\n\t\t\t<input type=\"hidden\" name=\"post_id\" value=\"19253\"\/>\n\t\t\t<input type=\"hidden\" name=\"form_id\" value=\"ca311cc\"\/>\n\t\t\t<input type=\"hidden\" name=\"referer_title\" value=\"\" \/>\n\n\t\t\t\n\t\t\t<div class=\"elementor-form-fields-wrapper elementor-labels-\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-field-type-text elementor-field-group elementor-column elementor-field-group-name elementor-col-100\">\n\t\t\t\t\t\t\t\t\t\t\t\t<label for=\"form-field-name\" class=\"elementor-field-label elementor-screen-only\">\n\t\t\t\t\t\t\t\tN\u00e1zov\t\t\t\t\t\t\t<\/label>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<input size=\"1\" type=\"text\" name=\"form_fields[name]\" id=\"form-field-name\" class=\"elementor-field elementor-size-sm  elementor-field-textual\" placeholder=\"N\u00e1zov\">\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<div class=\"elementor-field-type-tel elementor-field-group elementor-column elementor-field-group-field_f418624 elementor-col-100\">\n\t\t\t\t\t\t\t\t\t\t\t\t<label for=\"form-field-field_f418624\" class=\"elementor-field-label elementor-screen-only\">\n\t\t\t\t\t\t\t\tTelef\u00f3n\t\t\t\t\t\t\t<\/label>\n\t\t\t\t\t\t\t\t<input size=\"1\" type=\"tel\" name=\"form_fields[field_f418624]\" id=\"form-field-field_f418624\" class=\"elementor-field elementor-size-sm  elementor-field-textual\" placeholder=\"Telef\u00f3n\" pattern=\"[0-9()#&amp;+*-=.]+\" title=\"Pros\u00ed zad\u00e1vajte iba \u010d\u00edsla alebo tieto znaky #, -, *,\">\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<div class=\"elementor-field-type-email elementor-field-group elementor-column elementor-field-group-email elementor-col-100 elementor-field-required\">\n\t\t\t\t\t\t\t\t\t\t\t\t<label for=\"form-field-email\" class=\"elementor-field-label elementor-screen-only\">\n\t\t\t\t\t\t\t\tE-mail\t\t\t\t\t\t\t<\/label>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<input size=\"1\" type=\"email\" name=\"form_fields[email]\" id=\"form-field-email\" class=\"elementor-field elementor-size-sm  elementor-field-textual\" placeholder=\"E-mail\" required=\"required\">\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<div class=\"elementor-field-group elementor-column elementor-field-type-submit elementor-col-100 e-form__buttons\">\n\t\t\t\t\t<button class=\"elementor-button elementor-size-sm\" type=\"submit\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-angle-right\" viewbox=\"0 0 256 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M224.3 273l-136 136c-9.4 9.4-24.6 9.4-33.9 0l-22.6-22.6c-9.4-9.4-9.4-24.6 0-33.9l96.4-96.4-96.4-96.4c-9.4-9.4-9.4-24.6 0-33.9L54.3 103c9.4-9.4 24.6-9.4 33.9 0l136 136c9.5 9.4 9.5 24.6.1 34z\"><\/path><\/svg>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Okam\u017eite sa s nami spojte<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/button>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<input type=\"hidden\" name=\"trp-form-language\" value=\"sk\"\/><\/form>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/main>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-34618f0\" data-id=\"34618f0\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-5cb5173 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"5cb5173\" data-element_type=\"section\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-603fd00\" data-id=\"603fd00\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-237e243 elementor-widget elementor-widget-heading\" data-id=\"237e243\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Bro\u017e\u00fara<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-46b5b40 elementor-widget elementor-widget-text-editor\" data-id=\"46b5b40\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u010eal\u0161ie inform\u00e1cie, ako s\u00fa spr\u00e1vy o certifik\u00e1cii v\u00fdrobkov, anal\u00fdzy kvality, TDS a MSDS, n\u00e1jdete v na\u0161ej bro\u017e\u00fare.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-282ef89 elementor-widget__width-auto elementor-widget elementor-widget-button\" data-id=\"282ef89\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"#elementor-action%3Aaction%3Dpopup%3Aopen%26settings%3DeyJpZCI6IjE1MTkiLCJ0b2dnbGUiOmZhbHNlfQ%3D%3D\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Stiahnite si bro\u017e\u00faru<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-c328c37 elementor-search-form--skin-classic elementor-search-form--button-type-icon elementor-search-form--icon-search elementor-widget elementor-widget-search-form\" data-id=\"c328c37\" data-element_type=\"widget\" data-settings=\"{&quot;skin&quot;:&quot;classic&quot;,&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"search-form.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<search role=\"search\">\n\t\t\t<form class=\"elementor-search-form\" action=\"https:\/\/landu-china.com\/sk\/\" method=\"get\" data-trp-original-action=\"https:\/\/landu-china.com\/sk\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-search-form__container\">\n\t\t\t\t\t<label class=\"elementor-screen-only\" for=\"elementor-search-form-c328c37\">Vyh\u013eada\u0165<\/label>\n\n\t\t\t\t\t\n\t\t\t\t\t<input id=\"elementor-search-form-c328c37\" placeholder=\"Vyh\u013ead\u00e1vanie...\" class=\"elementor-search-form__input\" type=\"search\" name=\"s\" value=\"\">\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<button class=\"elementor-search-form__submit\" type=\"submit\" aria-label=\"Vyh\u013eada\u0165\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"e-font-icon-svg-container\"><svg class=\"fa fa-search e-font-icon-svg e-fas-search\" viewbox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M505 442.7L405.3 343c-4.5-4.5-10.6-7-17-7H372c27.6-35.3 44-79.7 44-128C416 93.1 322.9 0 208 0S0 93.1 0 208s93.1 208 208 208c48.3 0 92.7-16.4 128-44v16.3c0 6.4 2.5 12.5 7 17l99.7 99.7c9.4 9.4 24.6 9.4 33.9 0l28.3-28.3c9.4-9.4 9.4-24.6.1-34zM208 336c-70.7 0-128-57.2-128-128 0-70.7 57.2-128 128-128 70.7 0 128 57.2 128 128 0 70.7-57.2 128-128 128z\"><\/path><\/svg><\/div>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/button>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<input type=\"hidden\" name=\"trp-form-language\" value=\"sk\"\/><\/form>\n\t\t<\/search>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-136f28a e-con-full e-flex e-con e-child\" data-id=\"136f28a\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;,&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e05ee52 elementor-widget elementor-widget-heading\" data-id=\"e05ee52\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Kateg\u00f3rie produktov<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-23fcde2 elementor-align-left elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"23fcde2\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/landu-china.com\/sk\/produkty\/celuloza-landercoll\/\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Landercoll celul\u00f3za<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/landu-china.com\/sk\/produkty\/presny-redispergovatelny-polymerny-prasok\/\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Presn\u00e9 VAE-RDP<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/landu-china.com\/sk\/produkty\/novastar\/\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">NovaStar Chemicals<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/landu-china.com\/sk\/produkty\/pridavne-latky-v-potravinach\/\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Definova\u0165 potravin\u00e1rske chemik\u00e1lie<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/landu-china.com\/sk\/produkty\/uquick-farmaceuticke-medziprodukty\/\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Uquick Pharmaceutical Chemical<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-677b63d e-con-full e-flex e-con e-child\" data-id=\"677b63d\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;,&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-225a861 elementor-widget elementor-widget-heading\" data-id=\"225a861\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Trhy a rie\u0161enia<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ded0f19 elementor-align-left elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"ded0f19\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div 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33.941z\\&quot;&gt;&lt;\\\/path&gt;&lt;\\\/svg&gt;&quot;},&quot;motion_fx_motion_fx_mouse&quot;:&quot;yes&quot;,&quot;sticky&quot;:&quot;top&quot;,&quot;no_headings_message&quot;:&quot;No headings were found on this page.&quot;,&quot;hierarchical_view&quot;:&quot;yes&quot;,&quot;min_height&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;min_height_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;min_height_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;ekit_we_effect_on&quot;:&quot;none&quot;,&quot;sticky_on&quot;:[&quot;desktop&quot;,&quot;tablet&quot;,&quot;mobile&quot;],&quot;sticky_offset&quot;:0,&quot;sticky_effects_offset&quot;:0,&quot;sticky_anchor_link_offset&quot;:0}\" data-widget_type=\"table-of-contents.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-toc__header\">\n\t\t\t<h3 class=\"elementor-toc__header-title\">\n\t\t\t\tR\u00fdchle odkazy\t\t\t<\/h3>\n\t\t\t\t\t<\/div>\n\t\t<div id=\"elementor-toc__5f5a091\" class=\"elementor-toc__body\">\n\t\t\t<div class=\"elementor-toc__spinner-container\">\n\t\t\t\t<svg class=\"elementor-toc__spinner eicon-animation-spin e-font-icon-svg e-eicon-loading\" aria-hidden=\"true\" viewbox=\"0 0 1000 1000\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M500 975V858C696 858 858 696 858 500S696 142 500 142 142 304 142 500H25C25 237 238 25 500 25S975 237 975 500 763 975 500 975Z\"><\/path><\/svg>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Hydroxypropylmetylcelul\u00f3za (HPMC), univerz\u00e1lny polym\u00e9r zn\u00e1my svojimi v\u00fdnimo\u010dn\u00fdmi vlastnos\u0165ami, zohr\u00e1va vo farmaceutickom priemysle k\u013e\u00fa\u010dov\u00fa \u00falohu. Ako chemicky modifikovan\u00fd \u00e9ter celul\u00f3zy sa HPMC vyzna\u010duje stabilitou, biokompatibilitou a vynikaj\u00facimi filmotvorn\u00fdmi schopnos\u0165ami. V\u010faka t\u00fdmto vlastnostiam je HPMC preferovanou vo\u013ebou v \u0161irokom spektre farmaceutick\u00fdch pr\u00edpravkov, najm\u00e4 v peror\u00e1lnych liekov\u00fdch form\u00e1ch, [...]<\/p>","protected":false},"author":1,"featured_media":19257,"comment_status":"open","ping_status":"open","sticky":false,"template":"elementor_header_footer","format":"standard","meta":{"footnotes":""},"categories":[21,8],"tags":[22],"class_list":["post-19253","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pharmaceutical-insights","category-blog","tag-pharmaceutical-insights"],"_links":{"self":[{"href":"https:\/\/landu-china.com\/sk\/wp-json\/wp\/v2\/posts\/19253","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/landu-china.com\/sk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/landu-china.com\/sk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/landu-china.com\/sk\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/landu-china.com\/sk\/wp-json\/wp\/v2\/comments?post=19253"}],"version-history":[{"count":7,"href":"https:\/\/landu-china.com\/sk\/wp-json\/wp\/v2\/posts\/19253\/revisions"}],"predecessor-version":[{"id":19263,"href":"https:\/\/landu-china.com\/sk\/wp-json\/wp\/v2\/posts\/19253\/revisions\/19263"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/landu-china.com\/sk\/wp-json\/wp\/v2\/media\/19257"}],"wp:attachment":[{"href":"https:\/\/landu-china.com\/sk\/wp-json\/wp\/v2\/media?parent=19253"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/landu-china.com\/sk\/wp-json\/wp\/v2\/categories?post=19253"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/landu-china.com\/sk\/wp-json\/wp\/v2\/tags?post=19253"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}