{"id":19253,"date":"2024-11-13T16:40:02","date_gmt":"2024-11-13T08:40:02","guid":{"rendered":"https:\/\/landu-china.com\/?p=19253"},"modified":"2024-11-13T16:54:23","modified_gmt":"2024-11-13T08:54:23","slug":"hidroksipropilmetilceliuliozes-hpmc-naudojimas-farmacijoje","status":"publish","type":"post","link":"https:\/\/landu-china.com\/lt\/hidroksipropilmetilceliuliozes-hpmc-naudojimas-farmacijoje\/","title":{"rendered":"Hidroksipropilmetilceliulioz\u0117s (HPMC) naudojimas farmacijoje"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"19253\" class=\"elementor elementor-19253\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8ed4792 e-flex e-con-boxed e-con e-parent\" data-id=\"8ed4792\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-27bb47c5 e-con-full e-flex e-con e-child\" data-id=\"27bb47c5\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5745a1aa elementor-widget elementor-widget-heading\" data-id=\"5745a1aa\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Hidroksipropilmetilceliulioz\u0117s (HPMC) naudojimas farmacijoje<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5f276119 elementor-tablet-align-center elementor-widget elementor-widget-post-info\" data-id=\"5f276119\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"post-info.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-inline-items elementor-icon-list-items elementor-post-info\">\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-8a4e3ed elementor-inline-item\" itemprop=\"datePublished\">\n\t\t\t\t\t\t<a href=\"https:\/\/landu-china.com\/lt\/2024\/11\/13\/\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-far-calendar\" viewbox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M400 64h-48V12c0-6.6-5.4-12-12-12h-40c-6.6 0-12 5.4-12 12v52H160V12c0-6.6-5.4-12-12-12h-40c-6.6 0-12 5.4-12 12v52H48C21.5 64 0 85.5 0 112v352c0 26.5 21.5 48 48 48h352c26.5 0 48-21.5 48-48V112c0-26.5-21.5-48-48-48zm-6 400H54c-3.3 0-6-2.7-6-6V160h352v298c0 3.3-2.7 6-6 6z\"><\/path><\/svg>\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-date\">\n\t\t\t\t\t\t\t\t\t\t<time>13 lapkri\u010dio, 2024 m.<\/time>\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t<\/li>\n\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-271dd1a elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"271dd1a\" data-element_type=\"section\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<main class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-2d5bb40\" data-id=\"2d5bb40\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-38c4036 elementor-widget elementor-widget-text-editor\" data-id=\"38c4036\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Hidroksipropilmetilceliulioz\u0117 (HPMC) - universalus polimeras, pasi\u017eymintis i\u0161skirtin\u0117mis savyb\u0117mis, atlieka labai svarb\u0173 vaidmen\u012f farmacijos pramon\u0117je. Kaip chemi\u0161kai modifikuotas celiulioz\u0117s eteris, HPMC i\u0161siskiria stabilumu, biologiniu suderinamumu ir puikiomis pl\u0117vel\u0117s formavimo savyb\u0117mis. D\u0117l \u0161i\u0173 savybi\u0173 HPMC pasirenkamas \u012fvairiuose farmaciniuose preparatuose, ypa\u010d geriam\u0173j\u0173 dozi\u0173 formose, kontroliuojamo atpalaidavimo preparatuose ir apvalkaluose. \u0160iame straipsnyje aptarsime \u012fvairius HPMC naudojimo b\u016bdus, naud\u0105 ir funkcin\u012f pritaikym\u0105 farmacijos pramon\u0117je, i\u0161samiai paai\u0161kindami, kod\u0117l \u0161i med\u017eiaga taip pla\u010diai naudojama farmacijos pramon\u0117je.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2783d7f elementor-widget elementor-widget-heading\" data-id=\"2783d7f\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Kas yra HPMC? Trumpa ap\u017evalga<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-26892db elementor-widget elementor-widget-text-editor\" data-id=\"26892db\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>HPMC arba <strong>Hidroksipropilmetilceliulioz\u0117<\/strong>yra pusiau sintetinis, inerti\u0161kas ir vandenyje tirpus polimeras, gaunamas i\u0161 celiulioz\u0117s. Gaminamas apdorojant celiulioz\u0119 metilchloridu ir propileno oksidu, HPMC sudaro stabil\u0173 celiulioz\u0117s eter\u012f, kuris i\u0161laiko savo strukt\u016br\u0105 pla\u010diame pH diapazone ir \u012fvairiose temperat\u016brose. D\u0117l \u0161i\u0173 savybi\u0173 HPMC da\u017enai naudojamas farmaciniuose preparatuose, kuriems reikia stabilumo, nuoseklaus atpalaidavimo profilio ir pacientui palanki\u0173 savybi\u0173.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-56c3687 elementor-widget elementor-widget-heading\" data-id=\"56c3687\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">HPMC chemin\u0117s savyb\u0117s\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a15de8b elementor-widget elementor-widget-text-editor\" data-id=\"a15de8b\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>HPMC savyb\u0117s daro j\u012f unikal\u0173 tarp celiulioz\u0117s eteri\u0173. Pagrindin\u0117s jo savyb\u0117s yra \u0161ios:<\/p><ul><li><strong>Tirpumas:<\/strong> HPMC yra tirpus vandenyje, sudaro skaidr\u0173, didelio klampumo tirpal\u0105.<\/li><li><strong>Klampa:<\/strong> Klampumas reguliuojamas \u012fvairiose r\u016b\u0161yse, tod\u0117l tinka \u012fvairioms farmacin\u0117ms reikm\u0117ms.<\/li><li><strong>Termin\u0117 gelizacija:<\/strong> HPMC pasi\u017eymi terminiu geli\u0161kumu, tod\u0117l tam tikroje temperat\u016broje gali sudaryti gelius, o tai naudinga kontroliuojamo atpalaidavimo sistemose.<\/li><li><strong>pH stabilumas:<\/strong> HPMC i\u0161lieka stabilus skrand\u017eio ir \u017earnyno skys\u010diams b\u016bdingame pH lygyje, tod\u0117l tinka geriamiesiems vaistams tiekti.<\/li><\/ul><p>HPMC chemin\u0117 strukt\u016bra suteikia jam lankstumo naudojant ir veikiant, tod\u0117l jis yra labai svarbus ingredientas farmacijos sektoriuje.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-830780d elementor-widget elementor-widget-heading\" data-id=\"830780d\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">HPMC panaudojimas farmacijoje\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b097541 elementor-widget elementor-widget-heading\" data-id=\"b097541\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">1. Kontroliuojamo atpalaidavimo matric\u0173 sistemos<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4496db9 elementor-widget elementor-widget-text-editor\" data-id=\"4496db9\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>HPMC pla\u010diai naudojamas kontroliuojamo atpalaidavimo preparatuose. D\u0117l jo geb\u0117jimo hidratuojant formuoti gelius galima u\u017etikrinti ilgalaik\u012f veikli\u0173j\u0173 farmacini\u0173 med\u017eiag\u0173 (VFA) atpalaidavim\u0105. Kaip hidrofilin\u0117 matricos med\u017eiaga, HPMC, susid\u016br\u0119s su vir\u0161kinamojo trakto skys\u010diais, i\u0161brinksta, sudarydamas gelio barjer\u0105, kuris sul\u0117tina vaisto i\u0161siskyrimo greit\u012f. \u0160i savyb\u0117 ypa\u010d vertinga vaistams, kuriems reikalingas ilgalaikis ar pastovus terapinis poveikis, gerinantis pacient\u0173 atitikt\u012f ir ma\u017einantis dozavimo da\u017enum\u0105.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-d9317fe elementor-section-boxed elementor-section-height-default elementor-section-height-default elementor-invisible\" data-id=\"d9317fe\" data-element_type=\"section\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;,&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-8837c1a\" data-id=\"8837c1a\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-056a3f3 elementor-widget elementor-widget-spacer\" data-id=\"056a3f3\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-8c060fb\" data-id=\"8c060fb\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f156195 elementor-widget elementor-widget-spacer\" data-id=\"f156195\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-610c6cf elementor-widget elementor-widget-heading\" data-id=\"610c6cf\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">2. Pl\u0117vel\u0117s dengimo med\u017eiaga<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-aa3b745 elementor-widget elementor-widget-text-editor\" data-id=\"aa3b745\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>D\u0117l pl\u0117vel\u0119 formuojan\u010di\u0173 HPMC savybi\u0173 jis puikiai tinka <strong>table\u010di\u0173 dengimas<\/strong>. Pl\u0117vel\u0117s dangos naudojamos veikliosioms med\u017eiagoms apsaugoti, stabilumui padidinti ir poliruotai i\u0161vaizdai suteikti. HPMC dangos taip pat padeda u\u017emaskuoti kar\u010di\u0173j\u0173 API skon\u012f ir palengvina rijim\u0105. Be to, \u0161ios dangos gali b\u016bti skirtos enteriniam atpalaidavimui, u\u017etikrinant, kad vaistas i\u0161tirpt\u0173 \u017earnyne, o ne skrandyje, o tai ypa\u010d naudinga vaistams, kurie yra jautr\u016bs r\u016bg\u0161tinei aplinkai.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-55f9fda elementor-widget elementor-widget-heading\" data-id=\"55f9fda\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">3. Table\u010di\u0173 ir kapsuli\u0173 ri\u0161amoji med\u017eiaga\n<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-aa4aede elementor-widget elementor-widget-text-editor\" data-id=\"aa4aede\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Kaip <strong>segtuvai<\/strong>, HPMC padeda sutvirtinti table\u010di\u0173 strukt\u016br\u0105, pagerina sanglaud\u0105 ir mechanin\u012f stiprum\u0105. Tai labai svarbu, kad tablet\u0117s b\u016bt\u0173 pakankamai kietos ir kartu i\u0161laikyt\u0173 tinkamas dezintegracijos savybes. HPMC ri\u0161amoji geba leid\u017eia u\u017etikrinti nuosekl\u0173 dozavim\u0105 ir vienodum\u0105, o tai labai svarbu farmacijos produktams.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8650f24 elementor-widget elementor-widget-heading\" data-id=\"8650f24\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">4. Emulsiklis ir stabilizatorius skystuose preparatuose<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2deb52e elementor-widget elementor-widget-text-editor\" data-id=\"2deb52e\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Svetain\u0117je <strong>suspensijos ir emulsijos<\/strong>, HPMC veikia kaip <strong>emulsiklis ir stabilizatorius<\/strong>u\u017etikrinant skyst\u0173 vaist\u0173 homogeni\u0161kum\u0105 ir stabilum\u0105. Jo geb\u0117jimas formuoti koloidines dispersijas padeda suspenduoti netirpias daleles, tod\u0117l galima tolygiai paskirstyti ir nuosekliai dozuoti.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-037b4ef elementor-widget elementor-widget-heading\" data-id=\"037b4ef\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">5. Bioadhezija, skirta gleivin\u0117s pristatymui\n<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b414dde elementor-widget elementor-widget-text-editor\" data-id=\"b414dde\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Vaist\u0173 pristatymas \u012f gleivin\u0119, <strong>HPMC veikia kaip bioadhezyvas<\/strong>, tod\u0117l vaistai gali prilipti prie gleivin\u0117s pavir\u0161iaus (pvz., burnos, nosies ar aki\u0173 gleivin\u0117s). \u0160i savyb\u0117 pagerina vaist\u0173 i\u0161silaikymo laik\u0105 vartojimo vietoje, pagerina absorbcij\u0105 ir biologin\u012f prieinamum\u0105, ypa\u010d vaist\u0173, kuri\u0173 sistemin\u0117 absorbcija yra ma\u017ea.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3c52c28 elementor-widget elementor-widget-heading\" data-id=\"3c52c28\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">HPMC naudojimo farmacijos preparatuose privalumai\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-af9365c elementor-widget elementor-widget-text-editor\" data-id=\"af9365c\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3><strong>Padidintas stabilumas<\/strong><\/h3><p>HPMC i\u0161lieka stabilus \u012fvairiomis laikymo s\u0105lygomis, apsaugodamas API nuo dr\u0117gm\u0117s ir aplinkos poky\u010di\u0173. \u0160is stabilumas yra labai svarbus norint i\u0161laikyti jautri\u0173 vaist\u0173 veiksmingum\u0105 ir pasiekti ilgesn\u012f j\u0173 galiojimo laik\u0105.<\/p><h3><strong>Biologinis suderinamumas<\/strong><\/h3><p>HPMC yra <strong>netoksi\u0161kas, nedirginantis<\/strong>, ir <strong>Biologi\u0161kai suderinamas<\/strong>tod\u0117l idealiai tinka naudoti farmacijoje. Jo inerti\u0161kumas suma\u017eina nepageidaujam\u0173 reakcij\u0173 rizik\u0105, tod\u0117l u\u017etikrinamas paciento saugumas ir komfortas, ypa\u010d vartojant l\u0117tin\u012f ar ilgalaik\u012f gydym\u0105.<\/p><h3><strong>Kontroliuojamas vaist\u0173 atpalaidavimas<\/strong><\/h3><p>HPMC termin\u0117s gelizacijos ir hidratacijos savyb\u0117s prisideda prie <strong>kontroliuojamas i\u0161leidimas<\/strong> mechanizmai. Moduliuodami preparatuose naudojamo HPMC klampum\u0105, farmacijos mokslininkai gali sukurti individual\u0173 atpalaidavimo profil\u012f, atitinkant\u012f terapinius reikalavimus.<\/p><h3><strong>Skonio maskavimas ir geresn\u0117 estetika<\/strong><\/h3><p>HPMC dangos leid\u017eia <strong>skonio maskavimas<\/strong> nemalonaus skonio vaist\u0173. Jie taip pat gali pagerinti estetin\u012f table\u010di\u0173 vaizd\u0105, kad jas b\u016bt\u0173 lengviau nuryti ir jos b\u016bt\u0173 priimtinesn\u0117s pacientams.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-34ed0ad elementor-widget elementor-widget-heading\" data-id=\"34ed0ad\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">HPMC r\u016b\u0161ys farmaciniam naudojimui\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cd8e2f2 elementor-widget elementor-widget-text-editor\" data-id=\"cd8e2f2\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>HPMC yra \u012fvairi\u0173 r\u016b\u0161i\u0173, suskirstyt\u0173 pagal klampum\u0105 ir pakaitinimo tip\u0105, tod\u0117l j\u012f galima naudoti pagal poreikius:<\/p><ul><li><strong>Ma\u017eo klampumo klas\u0117s<\/strong>: Paprastai naudojamas <strong>skysti preparatai<\/strong> ir kaip table\u010di\u0173 bei kapsuli\u0173 ri\u0161amosios med\u017eiagos.<\/li><li><strong>Vidutinio klampumo klas\u0117s<\/strong>: Da\u017enai naudojamas <strong>kontroliuojamo atpalaidavimo sistemos<\/strong> d\u0117l j\u0173 subalansuot\u0173 gelio formavimo savybi\u0173.<\/li><li><strong>Didelio klampumo klas\u0117s<\/strong>: Idealiai tinka <strong>pl\u0117velin\u0117s dangos<\/strong> ir ilgalaikio atpalaidavimo, kai reikia stiprios gelio matricos.<\/li><\/ul><p>Kiekviena r\u016b\u0161is naudojama tam tikriems tikslams ir suteikia lankstumo kuriant pageidaujam\u0173 savybi\u0173 farmacijos produktus.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-3b43c66 elementor-section-boxed elementor-section-height-default elementor-section-height-default elementor-invisible\" data-id=\"3b43c66\" data-element_type=\"section\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;,&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-56798be\" data-id=\"56798be\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-670ea93 elementor-widget elementor-widget-spacer\" data-id=\"670ea93\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-8770651\" data-id=\"8770651\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-356731a elementor-widget elementor-widget-spacer\" data-id=\"356731a\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-a56c512 elementor-widget elementor-widget-heading\" data-id=\"a56c512\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">HPMC ir kiti polimerai farmacijoje\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ade00fa e-con-full e-flex e-con e-child\" data-id=\"ade00fa\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b21bb1b elementor-widget elementor-widget-text-editor\" data-id=\"b21bb1b\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>HPMC turi kelet\u0105 privalum\u0173, palyginti su alternatyviais polimerais:<\/p><ul><li><strong>PVP (polivinilpirolidonas)<\/strong>: Nors PVP taip pat naudojamas kaip ri\u0161amoji med\u017eiaga, jis neturi ilgalaikio atpalaidavimo ir pl\u0117vel\u0117s formavimo savybi\u0173, kurias u\u017etikrina HPMC, ypa\u010d didelio klampumo produktuose.<\/li><li><strong>PEG (polietilenglikolis)<\/strong>: PEG tirpsta vandenyje, ta\u010diau j\u0173 mechaninis stiprumas ir stabilumas kietose dozi\u0173 formose n\u0117ra toks pat kaip HPMC.<\/li><li><strong>Eudragit polimerai<\/strong>: Jie da\u017enai naudojami \u017earnyno apvalkalams, ta\u010diau jiems tr\u016bksta bioadhezini\u0173 ir hidrofilini\u0173 matricos savybi\u0173, d\u0117l kuri\u0173 HPMC yra universalus \u012fvairiose vaist\u0173 tiekimo sistemose.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c37d892 elementor-widget elementor-widget-heading\" data-id=\"c37d892\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">HPMC naudojimo farmacijoje i\u0161\u0161\u016bkiai\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c79d32e elementor-widget elementor-widget-text-editor\" data-id=\"c79d32e\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3><strong>Formuliavimo i\u0161\u0161\u016bkiai<\/strong><\/h3><p>Kontroliuojamo atpalaidavimo vaistams su HPMC gaminti reikia tikslumo. Tokie veiksniai kaip HPMC koncentracija, vaisto tirpumas ir daleli\u0173 dydis turi \u012ftakos galutinio produkto veikimui.<\/p><h3><strong>I\u0161laidos<\/strong><\/h3><p>Auk\u0161tos kokyb\u0117s HPMC gali b\u016bti brangesnis u\u017e kitas pagalbines med\u017eiagas, ta\u010diau jo privalumai kontroliuojamo atpalaidavimo preparatuose, stabilumas ir pacient\u0173 patogumas da\u017enai nusveria i\u0161laidas.<\/p><h3><strong>Gelio sluoksnio konsistencija<\/strong><\/h3><p>HPMC gelio sluoksnis yra labai svarbus kontroliuojamam atpalaidavimui, ta\u010diau jis turi b\u016bti kruop\u0161\u010diai valdomas. Jei gelis susidaro nenuosekliai, gali sutrikti vaisto atpalaidavimo greitis. Ta\u010diau, kruop\u0161\u010diai formuluojant, \u0161\u012f i\u0161\u0161\u016bk\u012f galima suvaldyti.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0b837a0 elementor-widget elementor-widget-heading\" data-id=\"0b837a0\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">HPMC ateitis farmacijoje\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0d79a84 elementor-widget elementor-widget-text-editor\" data-id=\"0d79a84\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3><strong>Nanotechnologij\u0173 taikymas<\/strong><\/h3><p>HPMC biologinio suderinamumo d\u0117ka jis yra perspektyvus <strong>nanodaleli\u0173 pagrindu sukurtos vaist\u0173 tiekimo sistemos<\/strong>. \u0160ios sistemos pagerina vaist\u0173 \u012fsisavinim\u0105, tod\u0117l jie tampa veiksmingesni, ypa\u010d sud\u0117ting\u0173 gydymo b\u016bd\u0173 atveju.<\/p><h3><strong>Tvari gamyba<\/strong><\/h3><p>Kadangi tvarumui skiriama vis daugiau d\u0117mesio, \u012fmon\u0117s ie\u0161ko b\u016bd\u0173, kaip gaminti HPMC, darant ma\u017eesn\u012f poveik\u012f aplinkai. \u0160is pokytis apima ekologi\u0161kus gamybos procesus ir tvar\u0173 tiekim\u0105.<\/p><h3><strong>Personalizuota medicina<\/strong><\/h3><p>Sveikatos prie\u017ei\u016brai art\u0117jant prie <strong>individualizuota medicina<\/strong>, HPMC pritaikomosios savyb\u0117s leid\u017eia j\u012f naudoti kuriant individualius vaist\u0173 profilius, pritaikytus individualiems paciento poreikiams.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c4f93d6 elementor-widget elementor-widget-spacer\" data-id=\"c4f93d6\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-718fb18 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"718fb18\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-9e8fcf0 elementor-section-boxed elementor-section-height-default elementor-section-height-default elementor-invisible\" data-id=\"9e8fcf0\" data-element_type=\"section\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;,&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-0af88b8\" data-id=\"0af88b8\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6ffd5ff elementor-widget elementor-widget-heading\" data-id=\"6ffd5ff\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Susisiekite su mumis ir gaukite nemokam\u0173 pavyzd\u017ei\u0173<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c66d934 elementor-widget elementor-widget-text-editor\" data-id=\"c66d934\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tSusisiekite su manimi d\u0117l naujausios kainos arba pra\u0161ymo atlikti bandom\u0105j\u012f test\u0105 (m\u016bs\u0173 bandiniai yra nemokami ir apima pristatym\u0105).\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ca311cc elementor-button-align-stretch elementor-widget elementor-widget-form\" data-id=\"ca311cc\" data-element_type=\"widget\" data-settings=\"{&quot;step_next_label&quot;:&quot;Next&quot;,&quot;step_previous_label&quot;:&quot;Previous&quot;,&quot;button_width&quot;:&quot;100&quot;,&quot;step_type&quot;:&quot;number_text&quot;,&quot;step_icon_shape&quot;:&quot;circle&quot;,&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"form.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<form class=\"elementor-form\" method=\"post\" name=\"New Form\" action=\"\">\n\t\t\t<input type=\"hidden\" name=\"post_id\" value=\"19253\"\/>\n\t\t\t<input type=\"hidden\" name=\"form_id\" value=\"ca311cc\"\/>\n\t\t\t<input type=\"hidden\" name=\"referer_title\" value=\"\" \/>\n\n\t\t\t\n\t\t\t<div class=\"elementor-form-fields-wrapper elementor-labels-\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-field-type-text elementor-field-group elementor-column elementor-field-group-name elementor-col-100\">\n\t\t\t\t\t\t\t\t\t\t\t\t<label for=\"form-field-name\" class=\"elementor-field-label elementor-screen-only\">\n\t\t\t\t\t\t\t\tPavadinimas\t\t\t\t\t\t\t<\/label>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<input size=\"1\" type=\"text\" name=\"form_fields[name]\" id=\"form-field-name\" class=\"elementor-field elementor-size-sm  elementor-field-textual\" placeholder=\"Pavadinimas\">\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<div class=\"elementor-field-type-tel elementor-field-group elementor-column elementor-field-group-field_f418624 elementor-col-100\">\n\t\t\t\t\t\t\t\t\t\t\t\t<label for=\"form-field-field_f418624\" class=\"elementor-field-label elementor-screen-only\">\n\t\t\t\t\t\t\t\tTelefonas\t\t\t\t\t\t\t<\/label>\n\t\t\t\t\t\t\t\t<input size=\"1\" type=\"tel\" name=\"form_fields[field_f418624]\" id=\"form-field-field_f418624\" class=\"elementor-field elementor-size-sm  elementor-field-textual\" placeholder=\"Telefonas\" pattern=\"[0-9()#&amp;+*-=.]+\" title=\"Priimami tik skai\u010diai ir telefono simboliai (#, -, * ir kt.).\">\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<div class=\"elementor-field-type-email elementor-field-group elementor-column elementor-field-group-email elementor-col-100 elementor-field-required\">\n\t\t\t\t\t\t\t\t\t\t\t\t<label for=\"form-field-email\" class=\"elementor-field-label elementor-screen-only\">\n\t\t\t\t\t\t\t\tEl. pa\u0161tas\t\t\t\t\t\t\t<\/label>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<input size=\"1\" type=\"email\" name=\"form_fields[email]\" id=\"form-field-email\" class=\"elementor-field elementor-size-sm  elementor-field-textual\" placeholder=\"El. pa\u0161tas\" required=\"required\">\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<div class=\"elementor-field-group elementor-column elementor-field-type-submit elementor-col-100 e-form__buttons\">\n\t\t\t\t\t<button class=\"elementor-button elementor-size-sm\" type=\"submit\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-angle-right\" viewbox=\"0 0 256 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M224.3 273l-136 136c-9.4 9.4-24.6 9.4-33.9 0l-22.6-22.6c-9.4-9.4-9.4-24.6 0-33.9l96.4-96.4-96.4-96.4c-9.4-9.4-9.4-24.6 0-33.9L54.3 103c9.4-9.4 24.6-9.4 33.9 0l136 136c9.5 9.4 9.5 24.6.1 34z\"><\/path><\/svg>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Nedelsiant susisiekite su mumis<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/button>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<input type=\"hidden\" name=\"trp-form-language\" value=\"lt\"\/><\/form>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/main>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-34618f0\" data-id=\"34618f0\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-5cb5173 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"5cb5173\" data-element_type=\"section\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-603fd00\" data-id=\"603fd00\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-237e243 elementor-widget elementor-widget-heading\" data-id=\"237e243\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Bro\u0161i\u016bra<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-46b5b40 elementor-widget elementor-widget-text-editor\" data-id=\"46b5b40\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Nor\u0117dami gauti daugiau informacijos, pvz., gamini\u0173 sertifikavimo ataskaitas, kokyb\u0117s analiz\u0119, TDS ir MSDS, atsisi\u0173skite m\u016bs\u0173 bro\u0161i\u016br\u0105.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-282ef89 elementor-widget__width-auto elementor-widget elementor-widget-button\" data-id=\"282ef89\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"#elementor-action%3Aaction%3Dpopup%3Aopen%26settings%3DeyJpZCI6IjE1MTkiLCJ0b2dnbGUiOmZhbHNlfQ%3D%3D\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Atsisi\u0173sti bro\u0161i\u016br\u0105<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-c328c37 elementor-search-form--skin-classic elementor-search-form--button-type-icon elementor-search-form--icon-search elementor-widget elementor-widget-search-form\" data-id=\"c328c37\" data-element_type=\"widget\" data-settings=\"{&quot;skin&quot;:&quot;classic&quot;,&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"search-form.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<search role=\"search\">\n\t\t\t<form class=\"elementor-search-form\" action=\"https:\/\/landu-china.com\/lt\/\" method=\"get\" data-trp-original-action=\"https:\/\/landu-china.com\/lt\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-search-form__container\">\n\t\t\t\t\t<label class=\"elementor-screen-only\" for=\"elementor-search-form-c328c37\">Paie\u0161ka<\/label>\n\n\t\t\t\t\t\n\t\t\t\t\t<input id=\"elementor-search-form-c328c37\" placeholder=\"Paie\u0161ka...\" class=\"elementor-search-form__input\" type=\"search\" name=\"s\" value=\"\">\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<button class=\"elementor-search-form__submit\" type=\"submit\" aria-label=\"Paie\u0161ka\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"e-font-icon-svg-container\"><svg class=\"fa fa-search e-font-icon-svg e-fas-search\" viewbox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M505 442.7L405.3 343c-4.5-4.5-10.6-7-17-7H372c27.6-35.3 44-79.7 44-128C416 93.1 322.9 0 208 0S0 93.1 0 208s93.1 208 208 208c48.3 0 92.7-16.4 128-44v16.3c0 6.4 2.5 12.5 7 17l99.7 99.7c9.4 9.4 24.6 9.4 33.9 0l28.3-28.3c9.4-9.4 9.4-24.6.1-34zM208 336c-70.7 0-128-57.2-128-128 0-70.7 57.2-128 128-128 70.7 0 128 57.2 128 128 0 70.7-57.2 128-128 128z\"><\/path><\/svg><\/div>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/button>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<input type=\"hidden\" name=\"trp-form-language\" value=\"lt\"\/><\/form>\n\t\t<\/search>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-136f28a e-con-full e-flex e-con e-child\" data-id=\"136f28a\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;,&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e05ee52 elementor-widget elementor-widget-heading\" data-id=\"e05ee52\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Produkt\u0173 kategorijos<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-23fcde2 elementor-align-left elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"23fcde2\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/landu-china.com\/lt\/produktai\/landercoll-celiulioze\/\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Landercoll celiulioz\u0117<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/landu-china.com\/lt\/produktai\/tikslus-redisperguojamo-polimero-milteliai\/\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Tikslus VAE-RDP<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/landu-china.com\/lt\/produktai\/novastar\/\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">\"NovaStar Chemicals<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/landu-china.com\/lt\/produktai\/maisto-priedai\/\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Apibr\u0117\u017eti maisto chemin\u0119 med\u017eiag\u0105<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/landu-china.com\/lt\/produktai\/uquick-farmaciniai-tarpiniai-produktai\/\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">\"Uquick Pharmaceutical Chemical<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-677b63d e-con-full e-flex e-con e-child\" data-id=\"677b63d\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;,&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-225a861 elementor-widget elementor-widget-heading\" data-id=\"225a861\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Rinkos ir sprendimai<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ded0f19 elementor-align-left elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"ded0f19\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/landu-china.com\/lt\/rinkos\/statyba-2\/\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Statybin\u0117 chemija<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/landu-china.com\/lt\/rinkos\/asmenine-prieziura-namuose\/\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Asmenin\u0117 ir nam\u0173 prie\u017ei\u016bra<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/landu-china.com\/lt\/rinkos\/farmacijos-pramone\/\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Farmacijos tarpiniai produktai<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/landu-china.com\/lt\/rinkos\/maisto-produktu-ir-gerimu-pramone\/\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Maisto priedai<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/landu-china.com\/lt\/rinkos\/daugiau-rinku\/\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Daugiau rink\u0173<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5f5a091 elementor-widget elementor-widget-table-of-contents\" data-id=\"5f5a091\" data-element_type=\"widget\" data-settings=\"{&quot;headings_by_tags&quot;:[&quot;h2&quot;],&quot;container&quot;:&quot;main&quot;,&quot;exclude_headings_by_selector&quot;:[],&quot;marker_view&quot;:&quot;bullets&quot;,&quot;icon&quot;:{&quot;value&quot;:&quot;fas fa-chevron-right&quot;,&quot;library&quot;:&quot;fa-solid&quot;,&quot;rendered_tag&quot;:&quot;&lt;svg class=\\&quot;e-font-icon-svg e-fas-chevron-right\\&quot; viewBox=\\&quot;0 0 320 512\\&quot; xmlns=\\&quot;http:\\\/\\\/www.w3.org\\\/2000\\\/svg\\&quot;&gt;&lt;path d=\\&quot;M285.476 272.971L91.132 467.314c-9.373 9.373-24.569 9.373-33.941 0l-22.667-22.667c-9.357-9.357-9.375-24.522-.04-33.901L188.505 256 34.484 101.255c-9.335-9.379-9.317-24.544.04-33.901l22.667-22.667c9.373-9.373 24.569-9.373 33.941 0L285.475 239.03c9.373 9.372 9.373 24.568.001 33.941z\\&quot;&gt;&lt;\\\/path&gt;&lt;\\\/svg&gt;&quot;},&quot;motion_fx_motion_fx_mouse&quot;:&quot;yes&quot;,&quot;sticky&quot;:&quot;top&quot;,&quot;no_headings_message&quot;:&quot;No headings were found on this page.&quot;,&quot;hierarchical_view&quot;:&quot;yes&quot;,&quot;min_height&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;min_height_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;min_height_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;ekit_we_effect_on&quot;:&quot;none&quot;,&quot;sticky_on&quot;:[&quot;desktop&quot;,&quot;tablet&quot;,&quot;mobile&quot;],&quot;sticky_offset&quot;:0,&quot;sticky_effects_offset&quot;:0,&quot;sticky_anchor_link_offset&quot;:0}\" data-widget_type=\"table-of-contents.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-toc__header\">\n\t\t\t<h3 class=\"elementor-toc__header-title\">\n\t\t\t\tGreitos nuorodos\t\t\t<\/h3>\n\t\t\t\t\t<\/div>\n\t\t<div id=\"elementor-toc__5f5a091\" class=\"elementor-toc__body\">\n\t\t\t<div class=\"elementor-toc__spinner-container\">\n\t\t\t\t<svg class=\"elementor-toc__spinner eicon-animation-spin e-font-icon-svg e-eicon-loading\" aria-hidden=\"true\" viewbox=\"0 0 1000 1000\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M500 975V858C696 858 858 696 858 500S696 142 500 142 142 304 142 500H25C25 237 238 25 500 25S975 237 975 500 763 975 500 975Z\"><\/path><\/svg>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Hidroksipropilmetilceliulioz\u0117 (HPMC) - universalus polimeras, pasi\u017eymintis i\u0161skirtin\u0117mis savyb\u0117mis, atlieka labai svarb\u0173 vaidmen\u012f farmacijos pramon\u0117je. Kaip chemi\u0161kai modifikuotas celiulioz\u0117s eteris, HPMC i\u0161siskiria stabilumu, biologiniu suderinamumu ir puikiomis pl\u0117vel\u0117s formavimo savyb\u0117mis. D\u0117l \u0161i\u0173 savybi\u0173 HPMC da\u017eniausiai naudojamas \u012fvairiuose farmaciniuose preparatuose, ypa\u010d geriam\u0173j\u0173 vaist\u0173 formose, o taip pat [...]<\/p>","protected":false},"author":1,"featured_media":19257,"comment_status":"open","ping_status":"open","sticky":false,"template":"elementor_header_footer","format":"standard","meta":{"footnotes":""},"categories":[21,8],"tags":[22],"class_list":["post-19253","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pharmaceutical-insights","category-blog","tag-pharmaceutical-insights"],"_links":{"self":[{"href":"https:\/\/landu-china.com\/lt\/wp-json\/wp\/v2\/posts\/19253","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/landu-china.com\/lt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/landu-china.com\/lt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/landu-china.com\/lt\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/landu-china.com\/lt\/wp-json\/wp\/v2\/comments?post=19253"}],"version-history":[{"count":7,"href":"https:\/\/landu-china.com\/lt\/wp-json\/wp\/v2\/posts\/19253\/revisions"}],"predecessor-version":[{"id":19263,"href":"https:\/\/landu-china.com\/lt\/wp-json\/wp\/v2\/posts\/19253\/revisions\/19263"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/landu-china.com\/lt\/wp-json\/wp\/v2\/media\/19257"}],"wp:attachment":[{"href":"https:\/\/landu-china.com\/lt\/wp-json\/wp\/v2\/media?parent=19253"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/landu-china.com\/lt\/wp-json\/wp\/v2\/categories?post=19253"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/landu-china.com\/lt\/wp-json\/wp\/v2\/tags?post=19253"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}